Why Coronary Anatomy & Physiology Are Not the Same

First and foremost, I hope this note finds you and your families safe and healthy.

During this time, all of us have been involved in significant learning and reeducation efforts.  This may mean cross-training in the ED or ICU, refocusing on system-wide planning, or simply adopting new ways to communicate with patients.

Like many of you, I have been using this time to participate and learn from online webinars. Professor Nick Curzen, chair of interventional cardiology at the University of Southampton and president of the British Cardiovascular Intervention Society, and Dr. Jonathon Leipsic1, a cardiac-focused radiologist in Vancouver, BC and past president of the Society of Cardiovascular CT, led a very informative session discussing the data and clinical experience which demonstrate the need for cardiologists to appreciate the differences between coronary anatomy and physiology and to understand the need to incorporate both elements in decision-making.

Several points stood out to me as Prof. Curzen and Dr. Leipsic comprehensively reviewed the vast clinical literature on this topic including study data on thousands of patients:

These clear improvements in clinical outcomes that result from applying physiology to clinical decision making is at the heart of why physicians have chosen the HeartFlow FFRct Analysis for over 50,000 patients.

If you would like to review some of the highlights of this session, or the session in its entirety, you can find the link here. I am confident you will find insights that will impact your daily clinical work.

View the Highlights

— A perspective from HeartFlow Chief Medical Officer, Campbell Rogers, MD
Bio | LinkedIn

1. Dr. Leipsic also serves as a paid consultant to HeartFlow providing guidance on medical education and science.
2. Curzen, et al. Circ Interven 2014. Tonino, et al. J Am Coll Cardiol 2010. Berry, et al. Euro Heart J 2014. Toth, et al. Euro Heart J 2014.
3. Curzen, et al. Circ Interven 2014. Curzen, et al. J Am Coll Cardiol Img 2016. Patel, et al. J Am Coll Cardiol Img 2019.
4. Parikh, et al. J Am Coll Cardiol 2020.

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HeartFlow FFRCT 分析は、有資格の臨床医による臨床的に安定した症状のある冠状動脈疾患患者への使用を目的とした個別化された心臓検査です。 HeartFlow Analysis によって提供される情報は、資格のある臨床医が患者の病歴、症状、その他の診断検査、および臨床医の専門的判断と組み合わせて使用​​することを目的としています。


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The HeartFlow FFRCT Analysis is a personalized cardiac test indicated for use in clinically stable symptomatic patients with coronary artery disease by qualified clinicians. The information provided by the HeartFlow Analysis is intended to be used by qualified clinicians in conjunction with the patient’s history, symptoms, and other diagnostic tests, as well as the clinician’s professional judgement.

For additional indication information about the HeartFlow Analysis, please visit www.heartflow.com/indications.

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Campbell Rogers, M.D., F.A.C.C.

Executive Vice President and Chief Medical Officer

Campbell brings a wealth of experience to HeartFlow, where he serves as the Chief Medical Officer. Prior to joining HeartFlow, he was the Chief Scientific Officer and Global Head of Research and Development at Cordis Corporation, Johnson & Johnson, where he was responsible for leading investments and research in cardiovascular devices. Prior to Cordis, he was Associate Professor of Medicine at Harvard Medical School and the Harvard-M.I.T. Division of Health Sciences and Technology, and Director of the Cardiac Catheterization and Experimental Cardiovascular Interventional Laboratories at Brigham and Women’s Hospital. He served as Principal Investigator for numerous interventional cardiology device, diagnostic, and pharmacology trials, is the author of numerous journal articles, chapters, and books in the area of coronary artery and other cardiovascular diseases, and was the recipient of research grant awards from the NIH and AHA.

He received his A.B. from Harvard College and his M.D. from Harvard Medical School.