Heartflow Plaque Staging
Know the Stage.
Manage with Precision.
Only with Heartflow Plaque Staging.*

Heartflow Plaque Staging is the only AI-powered risk stratification tool that quantifies and stages Total Plaque Volume (TPV) from an existing CCTA, delivering a precise, actionable assessment of coronary artery disease (CAD).

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Risk Stratification, Built on Total Plaque Volume.

Most risk goes unseen. Total Plaque Volume, an independent predictor of major cardiac events, reveals the true extent of coronary artery disease that traditional screening can miss.
Nearly
50
of heart attack patients are labeled as “low risk” using traditional risk assessments.1
7.3x (1)
risk of events in high vs. 
low total plaque cohort
Plaque is a strong predictor of MI irrespective of CV risk score, CAC, or stenosis (SCOT-HEART).2,3

Insights Built for Action in the DECIDE Registry

Medical management recommendations developed by preventive cardiology and CCTA expert consensus are being studied in the DECIDE Registry, the largest prospective registry on Plaque Analysis.4
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*Consider intensifying to next stage if nomogram percentile >50th and/or risk enhancers.5

See the Stage.
Understand the Risk.

TPV, an independent predictor of events, helps predict risk where stenosis, FFRct and traditional risk factors don’t. 6-8

Backed by the 
Strongest Data. 6-8

Validated in the FISH&CHIPS 8K clinical study and Mass General Brigham CCTA registry. More than 23,000 patients. Up to 16 years of follow-up.
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A Seamless,
Integrated Experience.
At Your Fingertips.

Plaque Staging is integrated directly within the Heartflow workflow. No additional steps, no separate platform.


How it works


Visualize, Characterize, and Quantify with the Interactive UI.

The interactive visualization allows healthcare professionals to explore detailed coronary anatomy and identify potential risk factors with unprecedented precision.



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The 3D model, straightened vessel, and cross-sectional views are anatomically co-registered.



How it works


Downloadable PDF Report for Each Patient.

Review personalized models and plaque volumes to drive change in patient behavior.

See How Heartflow Plaque Staging Can Change the Way You Assess and Manage CAD Risk.